|
CLINICAL APPLICATION OF MAGNETIC AND ELECTROMAGNETIC FIELDSM.S. Markov Biolelectrochemistry Laboratory, Mount Sinai School of Medicine, New York and Magnetherapy Inc., North Palm Beach, Florida Presentation at the 9th International Congress on Stress, Montreux, Switzerland February 16 - 22, 1997 Numerous publications suggest that exogenous magnetic and electromagnetic field can have a profound effect on a large number of biological systems. Some of these may be harmful, but others can provide significant benefits. Over the past few decades, magnetic and electromagnetic fields have been increasingly utilized for the treatment of various musculoskeletal injuries. The most effective clinical application of these physical modalities has been to accelerate the healing of bone fractures, reuniting those in which union has not taken place after years, as well as the reduction of edema and pain. Edema is an unavoidable consequence of musculoskeletal and soft tissue trauma, as well as inflammation due to disease. However, it interferes with the healing process, causing problems in patients recovering from surgical procedures, trauma or with chronic wounds and inflammation, and often produces pain. The ability to safely and effectively reduce edema can promote natural healing processes, increase the delivery of higher concentrations of antibiotics and other medications to affected tissues, and markedly reduce pain and edema. This paper will review decades of clinical application of low frequency pulsed electromagnetic fields (PEMF), pulsed radio frequency signals (PRF), millimeter waves (MMW) and static magnetic fields (SMF). It will include publications not only available from The National Library of Medicine and other commonly used databases, but also from Eastern Europe and Russia. Much of the pioneering research that has been conducted in these countries has not been readily available to Western Scientists for various reasons. Hundreds of thousands of patients have been treated worldwide with selected electromagnetic and magnetic fields having a success rate of approximately 80% with virtually no reported complications. Non invasive electromagnetic fields are now a common part of the orthopedist's armamentarium for the care of fresh and delayed fractures. Numerous clinical studies, in vivo animals experiments and in vitro cellular and membrane research, all suggest that magnetic and electromagnetic field stimulation can accelerate the healing processes. They are also able to enhance such fundamental properties of the human organism as repair and regeneration. It is clear now that endogenous electromagnetic and magnetic interactions are associated with many basic physiological processes ranging from ion binding and molecular conformation in the cell membrane to the macroscopic mechanical properties of tissues. The basic science data provides a background information for searching the mechanisms of coupling of magnetic and electromagnetic field with the target tissues. PEMF in current clinical practice have been employed to treat delayed and non-union fractures, spinal fusion, rotor cuff tendonitis and avascular necrosis. PRF (27.12 MHz) has been reported as successful therapeutical agent for soft tissue injuries, wound healing, burn treatment and nerve regeneration. MMW have been successfully applied for stimulation of immune and endocrine systems. Static magnetic fields have been most frequently used for alleviation of pain and other conditions that respond to improved local circulation and reduction of edema. Very recent clinical data concerning application in plastic and reconstructive surgery of permanent magnets (Tectonic®) may markedly reduce edema and ecchymosis in post operative patients undergoing plastic or reconstructive surgery such as face lift and liposuction, as will be illustrated. To date, no well-established mechanism has been identified which can explain how weak magnetic and electromagnetic fields can affect signal transduction pathways and therefore trigger healing processes. The potential for electromagnetic fields to restore normalcy to disturbed biological systems seems enormous. Uncovering the mechanisms responsible for this may be a formidable challenge, but offers the promise of significantly advancing our understanding of communicative processes in the body at a physical/atomic level, rather than the current chemical/molecular level. This emerging paradigm is a theme that has been developed at past Congresses, and will play a crucial role in shaping 21st century medicine. |
| ||||||||||||||||||||||||||||||||||||||||||||||||